Lactobacillus Crispatus

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VB Health
September 28, 2023

What is Lactobacillus Crispatus?

Lactobacillus Crispatus is a rod-shaped bacterium that belongs to the genus Lactobacillus. This beneficial microorganism is particularly interesting because it can produce hydrogen peroxide (H2O2), a substance known for its antimicrobial properties. Naturally found in the vaginal environment as well as the vertebrate gastrointestinal tract, Lactobacillus Crispatus plays a crucial role in maintaining a balanced and healthy microbial ecosystem in the body.

Lactobacillus Crispatus for Vaginal Health

The vaginal environment is a delicate balance of various microbial species, which together contribute to the overall health and well-being of an individual. Lactobacillus Crispatus stands out as a dominant and beneficial species. When present, it aids in:

  • Preventing Infections: By producing hydrogen peroxide, it inhibits the growth of harmful pathogens, helping to protect the vagina from infections.
  • Maintaining pH Balance: A balanced vaginal pH is essential for a healthy vaginal environment. Lactobacillus Crispatus helps in maintaining the ideal pH, thus discouraging the growth of harmful bacteria.
  • Protection against bacterial vaginosis (BV): BV is a condition characterized by an imbalance in the vaginal flora, often with a marked reduction or absence of Lactobacillus species. The presence of Lactobacillus Crispatus can help prevent this condition by ensuring the vaginal environment remains stable.

CTV-05: The Probiotic Solution

Given the vital role that Lactobacillus Crispatus plays in vaginal health, researchers have identified a specific strain, known as CTV-05, which can be used as a probiotic treatment. Suitable for both premenopausal and postmenopausal women, particularly those who suffer from recurrent urinary tract infections, this strain offers promise in:

  • Treating and Preventing BV: Clinical trials have indicated that CTV-05 can effectively colonize the vagina, helping in both prevention and treatment of recurrent bacterial vaginosis and other genital infections.
  • Complementing Antibiotic Treatment: For those already suffering from an infection, the combined use of CTV-05 and antibiotics has been shown to be effective, ensuring not only the treatment of the infection but also the restoration and maintenance of a healthy vaginal flora.

Products like the LACTIN-V make use of CTV-05 gelatin suppository capsules, which are inserted into the vagina, allowing for direct colonization and support of the vaginal microbiota. Aside from prescription suppositories, the over the counter supplement Soaking Wet provides essential probiotics for vaginal health, including Lactobacillus Crispatus.

Scientific Use of Lactobacillus

The potential benefits of Lactobacillus Crispatus, much like Lactobacillus Rhamnosus, in vaginal health are undeniable. With the development of targeted probiotics like CTV-05, there is hope for millions of women worldwide who struggle with recurrent infections and bacterial imbalances. As science continues to explore the intricate world of our body's microbiota, the importance of these beneficial bacteria becomes more evident. It's a reminder that sometimes, nature, in its simplicity, offers the best solutions for our complex health challenges.

Sources

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891990/

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